Promiliad Biopharma is a privately funded company that was incorporated in 2002 to take advantage of research opportunities at the interface of synthetic chemistry and natural product fermentation. Research is currently conducted in Montana (Missoula) and Ohio (Athens). Promiliad has been successful in securing federal funding for its research programs, primarily through the STTR program, and has received over $1.5 million to date.

Currently active drug discovery programs are targeted against pathogenic organisms including Gram negative bacteria, antifungal agents and the protozoal pathogen Cryptosporidium that causes diarrheal disease in humans.